Concise review of machine perfusion in liver transplantation
نویسندگان
چکیده
منابع مشابه
Concise Review Advances in Bioartificial Liver Devices
Liver failure is the cause of death for over 30,000 patients each year in the United States alone.When this process occurs in healthy individuals with normal livers, it is termed acute liver failure (ALF). Loss of liver function that complicates chronic liver disease is termed acute-on-chronic liver failure. Liver transplantation is curative for ALF and acute-onchronic liver failure.1-6 Over th...
متن کاملMyocardial perfusion characteristics during machine perfusion for heart transplantation.
BACKGROUND Optimal parameters for machine perfusion preservation of hearts prior to transplantation have not been determined. We sought to define regional myocardial perfusion characteristics of a machine perfusion device over a range of conditions in a large animal model. METHODS Dog hearts were connected to a perfusion device (LifeCradle, Organ Transport Systems, Inc, Frisco, TX) and cold p...
متن کاملA simplified subnormothermic machine perfusion system restores ischemically damaged liver grafts in a rat model of orthotopic liver transplantation
UNLABELLED BACKGROUND Liver donor shortages stimulate the development of strategies that incorporate damaged organs into the donor pool. Herein we present a simplified machine perfusion system without the need for oxygen carriers or temperature control, which we validated in a model of orthotopic liver transplantation. METHODS Rat livers were procured and subnormothermically perfused with ...
متن کاملConcise Review: Liver Regenerative Medicine: From Hepatocyte Transplantation to Bioartificial Livers and Bioengineered Grafts.
Donor organ shortage is the main limitation to liver transplantation as a treatment for end-stage liver disease and acute liver failure. Liver regenerative medicine may in the future offer an alternative form of therapy for these diseases, be it through cell transplantation, bioartificial liver (BAL) devices, or bioengineered whole organ liver transplantation. All three strategies have shown pr...
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ژورنال
عنوان ژورنال: World Journal of Hepatology
سال: 2020
ISSN: 1948-5182
DOI: 10.4254/wjh.v12.i1.6